A single vibrissal column in the first somatosensory cortex of the mouse demonstrated with 2-deoxyglucose.
نویسندگان
چکیده
Single functional column activated by stimulation of C3 vibrissa was visualized in the mouse somatosensory cortex with 2-deo-xyglucose autoradiography. The column was cylindrical in shape and extended through the entire cortical thickness. The darkest labeling was found in layer IV, over the anatomical C3 vibrissal barrel. The functional column stretched horizontally over parts of adjacent barrels. A zone of low 2-deoxyglucose uptake surrounded the densly labeled area and covered the rest of the postero medial barrel subfield.
منابع مشابه
Supranumerary Barrels Develop in the Somatosensory Cortex of Mice, After the Implantation of the Vibrissal Follicle Parts Containing Large Numbers of Receptors
In the mouse whiskerpad there is a group of vibrissal follicles arranged in five rows, which are topologically represented in the contralateral somatosensory cortex by the barrelfield. Each vibrissal follicle is a specialized sensory organ containing a large number of receptors, mostly Merkel cells. In these experiments, the parts of the vibrissal follicles containing most of the receptors were...
متن کاملIn vivo functional mapping of single synapses in the vibrissal cortex of the mouse
Single neurons, which represent the elementary units of brain function, organize into larger circuits that integrate external and internal brain signals. To understand the operation of these cortical circuits it is essential to identify the functional connections among the neurons. Recently, in vivo two‐photon calcium imaging made it possible to identify the location of these connections by ima...
متن کاملNeuronal response properties of somatosensory cortex (layer IV) are modulated following experience dependent plasticity in c-fiber depleted rats
Previous studies have shown that the receptive field properties, spontaneous activity and spatio-temporal interactions of low-threshold mechanical somatosensory cells in the barrel cortex are influenced by C-fibers. In this study, we examined the effect of C-fiber depletion on response properties of barrel cortex neurons following experience dependent plasticity. Methods: In this study, exte...
متن کاملAltered sensory processing in the somatosensory cortex of the mouse mutant barrelless.
Mice homozygous for the barrelless (brl) mutation, mapped here to chromosome 11, lack barrel-shaped arrays of cell clusters termed "barrels" in the primary somatosensory cortex. Deoxyglucose uptake demonstrated that the topology of the cortical whisker representation is nevertheless preserved. Anterograde tracers revealed a lack of spatial segregation of thalamic afferents into individual barre...
متن کاملCellular organization of cortical barrel columns is whisker-specific.
The cellular organization of the cortex is of fundamental importance for elucidating the structural principles that underlie its functions. It has been suggested that reconstructing the structure and synaptic wiring of the elementary functional building block of mammalian cortices, the cortical column, might suffice to reverse engineer and simulate the functions of entire cortices. In the vibri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Acta neurobiologiae experimentalis
دوره 44 2 شماره
صفحات -
تاریخ انتشار 1984